You can use (Windows Management Instrumentation) like this: Dim mos As New ManagementObjectSearcher('SELECT * FROM Win32_PhysicalMedia') For Each mo As ManagementObject In mos.Get() Dim serial As String = mo('SerialNumber').ToString() Next Although, I've read about cases in which no serial number is returned using WMI. Another way to accomplish this would be through Platform Invocation Services (PInvoke). Article includes a download in which the author implements and to extract drive information through Interop services in VB.NET. To use either of the above outlined methods you will need ADMIN rights, a utility which seems to circumvent this can be found. If your feeling adventurous the C++/Win32 is available for you to peruse. (Check out the function 'ReadPhysicalDriveInNTWithZeroRights()').

I tried getting Hard disk and Motherboard Serial Number from my PC. It works good in Windows 7 and Above But same code in CMD does not working for Windows XP. It Shows O.E.M to be filled or Returns Nothing wmic diskdrive get name,serialnumber,model // This is cmd to get serial num In Windows XP It Returns Error for serialnumber wmic baseboard get product,Manufacturer,version,serialnumber // This is cmd to get MotherBoard serialnumber In Windows XP and Win 8 it returns in serialnumber Error like ' To be filled by O.E.M' Am looking for Best Pc Unique Id, which can return id or serialnumber for any OS and should be unique. Please help me Thank You.

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Get disk serial number using the file system object (Windows 95/98/ME/NT/2000/2003/XP). Get unique Hardware id from PC. Ask Question -1. CPU ID and MAC address based hardware ID and Hard Drive serial number. HWID are not recommended as a licencing system as it isn't accurate and not practical if the user changes computer or formats the drives etc. It is more recommended to use a certificate system or more complex.